范江霖 简历
西安医学院，基础医学部，教授
教育经历（从大学本科开始，按时间倒序排序；请列出攻读研究生学位阶段导
师姓名）：
1.1988/4–1992/3， 佐贺医科大学， 病理学， 博士， 导师：渡边照男
2.1983/7–1986/7， 中国医科大学， 病理解剖学， 硕士， 导师：陈铁镇
3.1978/3–1983/7， 延边大学， 医学院， 学士， 导师：
科研与学术工作经历（按时间倒序排序；如为在站博士后研究人员或曾进入博士后流动站（或工作站）从事研究，请列出合作导师姓名）：
1.2015/3-至今，西安医学院，病理解剖教研室，教授
2.2006/3-至今，日本山梨大学，医学系，教授
3.2001/1-2006/3，日本筑波大学，医学系，副教授
4.1995/6-2001/1，日本筑波大学，医学系，讲师
主持或参加科研项目（课题）及人才计划项目情况（按时间倒序排序）：
1. 范江霖，陕西省自然科学基金重点项目，2017JZ028，利用转基因和基因敲除家兔研究动脉粥样硬化发生机制，起止时间： 2017-01-01至2019-12-31，10万，在研，主持
2. 范江霖，国家自然科学基金面上项目，81770457，利用基因敲入家兔研究载脂蛋白A-II在动脉粥样硬化发生中的作用，起止时间：2018.01-2021.12，83万，在研，主持
代表性研究成果和学术奖励情况（每项均按时间倒序排序）
一、期刊论文
1.第一作者论文
(1) Fan, Jianglin(#)(*)，Kitajima, Shuji，Watanabe, Teruo，Xu, Jie，Zhang，Jifeng，Liu, Enqi，Chen, Y Eugene，Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine.，Pharmacol Ther，2015，146：104-119
(2) Fan, Jianglin(#)(*)，Watanabe, Teruo，Transgenic rabbits as therapeutic protein bioreactors and human disease models.，Pharmacol Ther，2003，99（3）：261-282
(3) Fan, Jianglin(#)(*)，Watanabe, Teruo，Inflammatory reactions in the pathogenesis of atherosclerosis，J Atheroscler Thromb，2003，10（2）：63-71
2.通讯作者论文（勿与第一作者论文重复）
(1) Li, Shen，Wang, Yan-ning，Niimi, Manabu，Ning, Bo，Chen, Yajie，Kang, Dedong，Wang, Ziyun，Yu, Qi，Waqar, Ahmed Bilal，Liu, Enqi，Zhang, Jifeng，Shiomi, Masashi，Chen, Y. Eugene，Jianglin Fan(*)，Angiotensin II destabilizes coronaryplaques in WHHL rabbits，Arterioscler Thromb Vasc Biol in press 2016
(2) Niimi, Manabu(#)，Yang, Dongshan，Kitajima, Shuji，Ning, Bo，Wang, Chuan，Li, Shen，Liu, Enqi，Zhang, Jifeng，Eugene Chen, Y，Fan, Jianglin(*)，ApoE knockout rabbits: A novel model for the study of human hyperlipidemia.，Atherosclerosis，2016，245：187-193。
(3) Ning, Bo，Wang, Xiaoyan，Yu, Ying，Waqar, Ahmed Bilal，Yu, Qi，Koike, Tomonari，Shiomi, Masashi，Liu, Enqi，Wang, Yifei，Fan, Jianglin(*)，High-fruct ose and high-fat diet-induced insulin resistance enhances atherosclerosis in Watanabe heritable hyperlipidemic rabbits.，Nutr Metab (Lond)，2015，12：30-30
(4) Fang, Chao(#)，Ning, Bo，Waqar, Ahmed Bilal，Niimi, Manabu，Li, Shen，Satoh, Kaneo，Shiomi, Masashi，Ye, Ting，Dong, Sijun，Fan, Jianglin(*)，Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits.，Journal of Applied Toxicology，2015，35（9）：1058-1070。
(5) Yu, Qi(#)，Liu, Zhengcao，Waqar, Ahmed Bilal，Ning, Bo，Yang, Xianghong，Shiomi, Masashi，Graham, Mark J，Crooke, Rosanne M，Liu, Enqi，Dong, Sijun，Fan, Jianglin(*)，Effects of antisense oligonucleotides against C-reactive protein on the development of atherosclerosis in WHHL rabbits.，Mediators Inflamm，2014，2014：979132-979132
(6) Torzewski, Michael(#)，Waqar, Ahmed Bilal，Animal,Fan, Jianglin(*), models of C-reactive protein.，Mediators Inflamm，2014，2014：683598-683598
(7) Li, Shen，Liang, Jingyan，Niimi, Manabu，Bilal Waqar, Ahmed，Kang, Dedong，Koike, Tomonari，Wang, Yingge，Shiomi, Masashi，Fan, Jianglin(*)，Probucol suppresses macrophage infiltration and MMP expression in atherosclerotic plaques of WHHL rabbits.，J Atheroscler Thromb，2014，21（7）：648-658
(8) Niimi, Manabu(#)，Keyamura, Yuka，Nozako, Masanori，Koyama, Takashi，Kohashi, Masayuki，Yasufuku, Reiko，Yoshikawa, Tomohiro，Fan, Jianglin(*)，Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits.，Lipids in Health and Disease，2013，12：166-166
(9) Wang, Yao(#)，Niimi, Manabu，Nishijima, Kazutoshi，Waqar, Ahmed Bilal，Yu, Ying，Koike, Tomonari，Kitajima, Shuji，Liu, Enqi，Inoue, Tomohiro，Kohashi, Masayuki，Keyamura, Yuka，Yoshikawa, Tomohiro，Zhang, Jifeng，Ma, Loretta，Zha, Xiaohui，Watanabe, Teruo，Asada, Yujiro，Chen, Y Eugene，Fan, Jianglin(*)，Human apolipoprotein A-II protects against diet-induced atherosclerosis in transgenic rabbits.，Arteriosclerosis, Thrombosis, and Vascular Biology，2013，33（2）：224-231
(10) Wang, Ziyun(#)，Li, Shen，Sun, Lidan，Liu, Zhenming，Fan, Jianglin(*)，Comparative analyses of lipoprotein lipase, hepatic lipase, and endothelial lipase, and their binding properties with known inhibitors.，PLos One，2013，8（8）：e72146-e72146
(11) Zhang, Jifeng(#)，Yu, Ying，Nakamura, Kae，Koike, Tomonari，Waqar,
Ahmed Bilal，Zhang, Xiaowei，Liu, Enqi，Nishijima, Kazutoshi，Kitajima, Shuji，Shiomi, Masashi，Qi, Zhongxia，Yu, Jingwei，Graham, Mark J，Crooke, Rosanne M，Ishida, Tatsuro，Hirata, Ken-Ichi，Hurt-Camejo, Eva，Chen, Y Eugene，Fan, Jianglin(*)，Endothelial lipase mediates HDL levels in normal and hyperlipidemic rabbits.，J Atheroscler Thromb，2012，19（3）：213-226
(12) Waqar, Ahmed Bilal(#)，Koike, Tomonari，Yu, Ying，Inoue, Tomohiro，Aoki, Tadashi，Liu, Enqi，Fan, Jianglin(*)，High-fat diet without excess calories induces metabolic disorders and enhances atherosclerosis in rabbits.，Atherosclerosis，2010，213（1）：148-155
(13) Koike, Tomonari(#)，Kitajima, Shuji，Yu, Ying，Nishijima, Kazutoshi，Zhang, Jifeng，Ozaki, Yukio，Morimoto, Masatoshi，Watanabe, Teruo，Bhakdi, Sucharit，Asada, Yujiro，Chen, Y Eugene，Fan, Jianglin(*)，Human C-reactive protein does not promote atherosclerosis in transgenic rabbits.，Circulation，2009，120（21）：2088-2094
(14) Koike, Tomonari(#)，Kitajima, Shuji，Yu, Ying，Li, Ying，Nishijima, Kazutoshi，Liu, Enqi，Sun, Huijun，Waqar, Ahmed Bilal，Shibata, Nobumitsu，Inoue, Tomoriho，Wang, Yao，Zhang, Bo，Kobayashi, Junji，Morimoto, Masatoshi，Saku, Keijiro，Watanabe, Teruo，Fan, Jianglin(*)，Expression of human apoAII in transgenic rabbits leads to dyslipidemia: a new model for combined hyperlipidemia.，Arterioscler Thromb Vasc Biol，2009，29（12）：2047-2053
(15) Yu, Ying(#)，Koike, Tomonari，Kitajima, Shuji，Liu, Enqi，Morimoto, Masatoshi，Shiomi, Masashi，Hatakeyama, Kinta，Asada, Yujiro，Wang, Ke-Yong，Sasaguri, Yasuyuki，Watanabe, Teruo，Fan, Jianglin(*)，Temporal and quantitative analysis of expression of metalloproteinases (MMPs) and their endogenous inhibitors in atherosclerotic lesions.，Histol Histopathol，2008，23（12）：1503-1516
(16) Shiomi, Masashi(#)(*)，Unstable coronary plaques and Fan, Jianglin(*),cardiac events in myocardial infarction-prone Watanabe heritable hyperlipidemic rabbits: questions and quandaries.，Current Opinion in Lipidology，2008，19（6）：631-636
(17) Kitajima, Shuji(#)，Jin, Yingji，Koike, Tomonari，Yu, Ying，Liu, Enqi，Shiomi, Masashi，Marcovina, Santica M，Morimoto, Masatoshi，Watanabe, Teruo，Fan, Jianglin(*)，Lp(a) enhances coronary atherosclerosis in transgenic Watanabe heritable hyperlipidemic rabbits.，Atherosclerosis，2007，193（2）：269-276
(18) Liu, Enqi(#)，Morimoto, Masatoshi，Kitajima, Shuji，Koike, Tomonari，Yu, Ying，Shiiki, Hideo，Nagata, Michio，Watanabe, Teruo，Fan, Jianglin(*)，Increased expression of vascular endothelial growth factor in kidney leads to progressive impairment of glomerular functions.，Journal of the American Society of Nephrology，2007，18（7）：2094-2104
(19) Liang, Jingyan(#)，Liu, Enqi，Yu, Ying，Kitajima, Shuji，Koike, Tomonari，Jin, Yingji，Morimoto, Masatoshi，Hatakeyama, Kinta，Asada, Yujiro，Watanabe, Teruo，Sasaguri, Yasuyuki，Watanabe, Shigeyuki，Fan, Jianglin(*)，Macrophage metalloelastase accelerates the progression of atherosclerosis in transgenic rabbits.，Circulation，2006，113（16）：1993-2001
(20) Kitajima, Shuji(#)，Liu, Enqi，Morimoto, Masatoshi，Koike, Tomonari，Yu, Ying，Watanabe, Teruo，Imagawa, Shigehiko，Fan, Jianglin(*)，Transgenic rabbits with increased VEGF expression develop hemangiomas in the liver: a new model for Kasabach-Merritt syndrome.，Laboratory Investigation，2005，85（12）：1517-1527
(21) Sun, Huijun(#)，Koike, Tomonari，Ichikawa, Tomonaga，Hatakeyama, Kinta，Shiomi, Masashi，Zhang, Bo，Kitajima, Shuji，Morimoto, Masatoshi，Watanabe, Teruo，Asada, Yujiro，Chen, Yuqing E，Fan, Jianglin(*)，Creactive protein in atherosclerotic lesions: its origin and pathophysiological significance.，American Journal Of Pathology，2005，167（4）：1139-1148
(22) Ichikawa, Tomonaga(#)，Liang, Jingyan，Kitajima, Shuji，Koike, Tomonari，Wang, Xiaofei，Sun, Huijun，Morimoto, Masatoshi，Shikama, Hisataka，Watanabe, Teruo，Yamada, Nobuhiro，Fan, Jianglin(*)，Macrophage-deriv ed lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits.，Atherosclerosis，2005，179（1）：87-95
(23) Koike, Tomonari(#)，Liang, Jingyan，Wang, Xiaofei，Ichikawa, Tomonaga，Shiomi, Masashi，Sun, Huijun，Watanabe, Teruo，Liu, George，Fan, Jianglin(*)，Enhanced aortic atherosclerosis in transgenic Watanabe heritable hyperlipidemic rabbits expressing lipoprotein lipase.，Cardiovascular Research，2005，65（2）：524-534
(24) Liu, Enqi(#)，Kitajima, Shuji，Higaki, Yasuki，Morimoto, Masatoshi，Sun, Huijun，Watanabe, Teruo，Yamada, Nobuhiro，Fan, Jianglin(*)，High lipoprotein lipase activity increases insulin sensitivity in transgenic rabbits.，Metabolism-Clinical and Experimental，2005，54（1）：132-138
(25) Wang, Xiaofei(#)，Liang, Jingyan，Koike, Tomonari，Sun, Huijun，Ichikawa, Tomonaga，Kitajima, Shuji，Morimoto, Masatoshi，Shikama, Hisataka，Watanabe, Teruo，Sasaguri, Yasuyuki，Fan, Jianglin(*)，Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits.，American Journal Of Pathology，2004，165（4）：1375-1383
(26) Koike, Tomonari(#)，Liang, Jingyan，Wang, Xiaofei，Ichikawa, Tomonaga，Shiomi, Masashi，Liu, George，Sun, Huijun，Kitajima, Shuji，Morimoto, Masatoshi，Watanabe, Teruo，Yamada, Nobuhiro，Fan, Jianglin(*)，Overexpression of lipoprotein lipase in transgenic Watanabe heritable hyperlipidemic rabbits improves hyperlipidemia and obesity，Journal of Biological Chemistry，2004，279（9）：7521-7529
3.既非第一作者又非通讯作者论文
(1) Zhao, Sihai(#)，Li, Yafeng，Gao, Shoucui，Wang, Xiaojing，Sun, Lijing，Cheng, Daxing，Bai, Liang，Guan, Hua，Wang, Rong，Fan, Jianglin，Liu,Enqi，Autocrine Human Urotensin II Enhances Macrophage-Derived Foam Cell Formation in Transgenic Rabbits.，Biomed Research International，2015，2015：843959-843959
(2) Yang, Dongshan(#)，Xu, Jie，Zhu, Tianqing, Lai,Fan, Jianglin,Liangxue，Zhang, Jifeng，Chen, Y Eugene，Effective gene targeting in rabbits using RNA-guided Cas9 nucleases.，J Mol Cell Biol，2014，6（1）：97-99
(3) Yang, Dongshan(#)，Zhang, Jifeng，Xu, Jie，Zhu, Tianqing，Fan, Yanbo，Fan, Jianglin，Chen, Y Eugene，Production of apolipoprotein C-III knockout rabbits using zinc finger nucleases.，J Vis Exp，2013，（81）：e50957-e50957
(4) Ding, Yinyuan(#)，Wang, Yuhui，Zhu, Hong，Fan, Jianglin, Yu, Liqing，Liu, George，Liu, Enqi，Hypertriglyceridemia and delayed clearance of fat load in transgenic rabbits expressing human apolipoprotein CIII.，Transgenic Research，2011，20（4）：867-875
(5) Pravenec, Michal(#)(*)，Kajiya, Takashi，Zidek, Vaclav，Landa, Vladimir，Mlejnek, Petr，Simakova, Miroslava，Silhavy, Jan，Malinska, Hana，Oliyarnyk, Olena，Kazdova, Ludmila，Fan, Jianglin，Wang, Jiaming，Kurtz, Theodore W，Effects of human C-reactive protein on pathogenesis of features of the metabolic syndrome.，Hypertension，2011，57（4）：731-737
(6) Shiomi, Masashi(#)(*)，Ito, Takashi，Yamada, Satoshi，Kawashima, Seinosuke，Fan, Jianglin，Development of an animal model for spontaneous myocardial infarction (WHHLMI rabbit).，Arterioscler Thromb Vasc Biol，2003，23（7）：1239-1244
